A2: Aspirin for PUD patients!

The correct answer for question no. 2 is: (False)

Explanation: Aspirin is one of the Non-steroidal Anti-inflammatory Drugs (NSAIDs) that shouldn’t be administered by peptic ulcer patients, although for patients with high cardiovascular risk (as in the case of primary cardiovascular risk prevention that is mentioned in the question) who require NSAIDs to prevent serious cardiovascular events one of the following options as in this table should be followed:

Use of NSAID for PUD patients – balancing cardiovascular and gastrointestinal risks

Part of Peptic Ulcer Disease Concept Map

Thus, for primary cardiovascular event prevention (question 2), the choice is made according to gastrointestinal (GI) risk and could be one of the following:

  1. for low GI risk: Naproxen + proton pump inhibitor or misoprostol.
  2. for moderate GI risk: Naproxen + proton pump inhibitor or misoprostol.
  3. for high GI risk: Avoid NSAIDs and COX2 inhibitors.

I hope you find this answer clear and informative.  Don’t hasitate to send me if you want more clarification.  And if like it please share it.


2 Responses to “A2: Aspirin for PUD patients!”

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